Ly-6G (Gr-1) Rat anti-Mouse, Clone: 1A8-Ly6g, Functional Grade, eBioscience™
Rat Monoclonal Antibody, Functional Grade
Brand: Affymetrix eBioscience 16-9668-85
Additional Details : Weight : 0.09500kg
DescriptionThe monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25kDa GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The ligand for Ly-6G is currently unknown.
Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity.
|aqueous buffer, no sodium azide|
|Store at 2-8°C.|