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Invitrogen™ Human MAP2K2 (MEK2), His Tag Recombinant Protein

Produktkod. 10502943
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Kvantitet:
1 mg
10 μg
Förpackningsstorlek:
10µg
1mg
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For Research Use Only. All usage must comply with product instructions.

Produktkod. 10502943

Brand: Invitrogen™ PV4005

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Denna artikel kan inte returneras. Se returpolicy

For Research Use Only. All usage must comply with product instructions.

Beskrivning

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that is known to play a critical role in mitogen growth factor signal transduction. Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P36507
Koncentration See Label
För användning med (applikation) Kinase Assay
Formulering 50mM tris HCl with 150mM NaCl, 0.5mM EDTA, 50% glycerol, 0.02% Triton X-100, 2mM DTT and no preservative; pH 7.5
Gen-ID (Entrez) 5605
Molekylvikt (g/mol) 49.5 kDa
Namn Human MAP2K2 (MEK2), His Tag
pH-intervall 7.5
Reningsmetod Purified
Kvantitet 1 mg
Förvaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
Vanligt namn MEK2
Gensymbol MAP2K2
KinaseFamily STE7 Kinase Family
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Protein Tag His-tag
Sekvens Full length
Innehåll och lagring -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser/Thr Kinases: STE Group
Frakt skick Dry Ice
Uttryckssystem Baculovirus
Proteinform Full Length
Form Liquid
Forskningskategori Drug Development
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