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Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein

Produktkod. 11593527
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Kvantitet:
10 μg
100 μg
Förpackningsstorlek:
100µg
10µg
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For Research Use Only. All usage must comply with product instructions.

Produktkod. 11593527

Brand: Invitrogen™ PV3788

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Denna artikel kan inte returneras. View return policy

For Research Use Only. All usage must comply with product instructions.

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length.

MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
TRUSTED_SUSTAINABILITY

Specifications

Tillträdesnummer Q16584
Koncentration See Label
För användning med (applikation) Kinase Assay
Formulering 50mM tris with 2mM DTT, 0.02% Triton X-100, 50% glycerol, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
Gen-ID (Entrez) 4296
Molekylvikt (g/mol) 120.1 kDa
Namn Human MAP3K11 (MLK3), GST Tag
pH-intervall 7.5
Reningsmetod Purified
Kvantitet 10 μg
Förvaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase
Vanligt namn MLK3
Gensymbol MAP3K11
KinaseFamily MLK Kinase Family
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Protein Tag GST-tag
Sekvens Full length
Innehåll och lagring -80°C, Avoid Freeze/Thaw Cycles
Analysinträde Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group Ser⁄Thr Kinases: TKL Group
Frakt skick Dry Ice
Systemkompatibilitet LanthaScreen™ Antibody, LanthaScreen™ Substrate, Omnia™ Bulk Substrate
Målinträde MAP3K11
Target Gene mitogen-activated protein kinase kinase kinase 11
Uttryckssystem Insect cells
Proteinfamilj Kinases & Inhibitors
Proteinform Recombinant, Full Length
Form Liquid
Protein subtyp Serine/Threonine Kinases
Forskningskategori Immunology, Oncology, Signal Transduction
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