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Eurofins DiscoverX MAPKAP Kinase 2 Protein, Active
Beskrivning
Mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MAPKAPK2) mediates multiple p38 MAPK-dependent inflammatory responses. This kinase can be activated in response to cellular stress and proinflammatory cytokines through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta.
GenBank NM_032960. The recombinant sequence is D116H (native co ordinates) with respect toGenBank NM_032960. This conflict is reported in SWISSPROT P49137. The cDNA also contains the translational conflict A399G, and a c-myc epitope at the C-terminus.
Specifikationer
Specifikationer
| Formulering | mg/mL of enzyme in 50 mM Tris/HCl, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 50% glycerol, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol, 5 mM dithiothreitol. Liquid at -20°C. |
| Molekylvikt (g/mol) | 70.2 kDa |
| Kvantitet | 10 μg |
| Art | Human |
| Rekombinant | Recombinant |
| Protein Tag | N-terminal GST |
| Uttryckssystem | Recombinant enzyme expressed in E. coli cells |
| Proteinform | Truncated |
| Renhet eller kvalitetsklass | ≥60% |
| Protein | MAPKAP Kinase 2, active |
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