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MD-2 Mouse anti-Human, Clone: 9B4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9928-80

Additional Details : Weight : 0.01000kg

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Product Code. 15258247

  • 1110.00 SEK / 25µg


Estimated Shipment date
from Supplier 26-03-2019
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Description

Description

MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Specifications

Specifications

MD-2
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9Y6Y9
MD-2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunoprecipitation
9B4
Unconjugated
LY96
Liquid
LY96
IgG1
25 μg
4° C
Primary
23643
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