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Tocris Bioscience™ Me VH 032, amine

Produktkod. 18707376
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Kvantitet:
100 mg
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Produktkod. Kvantitet
18707376 100 mg
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Produktkod. 18707376 Leverantör Tocris Bioscience™ Leverantörsnummer FAB9610U100UG

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Beskrivning

Amine functionalized VHL ligand for PROTAC™ research

Me VH 032, amine is a derivative of the von Hippel-Lindau (VHL) ligand, VH 032 for use as a precursor to a PROTAC® that hijacks VHL as the E3 ubiquitin ligase component. Me VH 032, amine is supplied with a primary amine functional handle, for ready conjugation to a linker/target protein ligand. Introduction of the methyl group at the benzylic position of VH 032 is associated with improved binding affinity.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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TRUSTED_SUSTAINABILITY

Specifikationer

Kemiskt namn eller material (4R)-3-Methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-L-prolinamide dihydrochloride
CAS 2504950-56-3
Kvantitet 100 mg
Mål Degrader Building Blocks
Molekylformel C23H32N4O3S.2HCl
Produkttitel
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