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Melatonin, 99+%
Description
Melatonin fungerar som ett neurohormon som uppreglerar antioxidantenzymer och hämmar råttans NOS1. Det fungerar också som en särskilt betydelsefull endogen antioxidant. Melatonin är en råtta NOS1 (nNOS)-hämmare. Melatonin är en aktiverare av MEL-1A-R och MEL-1B-R.
Denna Thermo Scientific Chemicals varumärkesprodukt var ursprungligen en del av produktportföljen Alfa Aesar . Viss dokumentation och etikettinformation kan hänvisa till det äldre varumärket. Den ursprungliga Alfa Aesar produkt-/artikelkoden eller SKU-referensen har inte ändrats som en del av varumärkesövergången till Thermo Scientific Chemicals.
General Description
• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities
• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities
Applications
• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1
• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R
• The production and secretion of melatonine are dependent on beta-adrenergic receptor function
• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor
• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells
• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression
Specifications
Specifications
| Kemiskt namn eller material | Melatonin |
| Smältpunkt | 116°C to 120°C |
| Färg | White |
| Kvantitet | 5 g |
| Beilstein | 205542 |
| Merck Index | 14,5816 |
| Löslighetsinformation | Soluble in ethanol to at least 50mg/ml |
| Formel vikt | 232.28 |
| Procent renhet | ≥99% |
| Fysisk form | Powder |
RUO– Endast forskningsanvändning
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