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Melatonin, 99+%

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Melatonin, 99%, CAS #73-31-4, är ett hormon som vanligtvis produceras i tallkottkörteln och frisätts i blodet. | CAS: 73-31-4 | C13H16N2O2 | 232,283 g/mol

Melatonin fungerar som ett neurohormon som uppreglerar antioxidantenzymer och hämmar råttans NOS1. Det fungerar också som en särskilt betydelsefull endogen antioxidant. Melatonin är en råtta NOS1 (nNOS)-hämmare. Melatonin är en aktiverare av MEL-1A-R och MEL-1B-R.

Denna Thermo Scientific Chemicals varumärkesprodukt var ursprungligen en del av produktportföljen Alfa Aesar . Viss dokumentation och etikettinformation kan hänvisa till det äldre varumärket. Den ursprungliga Alfa Aesar produkt-/artikelkoden eller SKU-referensen har inte ändrats som en del av varumärkesövergången till Thermo Scientific Chemicals.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities

• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1

• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R

• The production and secretion of melatonine are dependent on beta-adrenergic receptor function

• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor

• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells

• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 73-31-4
Molekylformel C13H16N2O2
Molekylvikt (g/mol) 232.283
MDL-nummer MFCD00005655
InChI-nyckel DRLFMBDRBRZALE-UHFFFAOYSA-N
Synonym melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine
PubChem CID 896
ChEBI CHEBI:16796
IUPAC-namn N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
LEDER CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

Specifications

Kemiskt namn eller material Melatonin
Smältpunkt 116°C to 120°C
Färg White
Kvantitet 5 g
Beilstein 205542
Merck Index 14,5816
Löslighetsinformation Soluble in ethanol to at least 50mg/ml
Formel vikt 232.28
Procent renhet ≥99%
Fysisk form Powder

RUO– Endast forskningsanvändning

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