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Eurofins DiscoverX Met Protein, Active
Beskrivning
MET tyrosine kinase is a high-affinity receptor for hepatocyte growth factor/scatter factor. Signaling via this receptor-ligand pair has been shown to affect a wide range of biological activities, including angiogenesis, cellular motility, growth, invasion, and morphogenic differentiation. Mutations in the MET tyrosine kinase receptor have been identified in both hereditary and sporadic forms of papillary renal carcinoma and implicated in tumor growth, invasion, and metastasis.
GenBank J02958. This construct contains the conflicts A1209G and V1290L with respect toGenBank J02958. Both conflicts are reported inGenBank BU595386, BQ315895 and BQ316491.
Specifikationer
Specifikationer
| Formulering | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molekylvikt (g/mol) | 50 kDa |
| Kvantitet | 10 μg |
| Art | Human |
| Rekombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Uttryckssystem | Recombinant enzyme expressed in Sf21 insect cells |
| Proteinform | Truncated |
| Renhet eller kvalitetsklass | ≥60% |
| Protein | Met, active |
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