MHC Class II (I-A/I-E) Rat anti-Mouse, Clone: M5/114.15.2, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-5321-81
Additional Details : Weight : 0.01000kg
DescriptionIt is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
|MHC Class II (I-A/I-E)|
|PBS with 0.09% sodium azide; pH 7.2|
|I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, MHC class 2, MHC class II glygoproteins|
|Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization, Western Blot|
For Research Use Only.