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Midostaurin, MedChemExpress

Produktkod. 16474796
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16474796 100 mg
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Produktkod. 16474796 Leverantör Medchem Express Leverantörsnummer HY10230

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Beskrivning

MedChemExpress Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects.

Midostaurin (PKC412

Specifikationer

Kemiskt namn eller material Midostaurin
CAS 120685-11-2
Färg White
Anteckningar om renhetsgrad Research
Molekylformel C35H30N4O4
Kvantitet 100 mg
Synonym PKC412 CGP 41251
Löslighetsinformation DMSO : 50 mg/mL (87.62 mM; Need ultrasonic)
LEDER O=C(C1=CC=CC=C1)N(C)[C@H]2[C@@H](OC)[C@@]3(C)N(C4=C5C=CC=C4)C6=C5C7=C(C(NC7)=O)C8=C6N(C9=CC=CC=C98)[C@@](O3)([H])C2
Molekylvikt (g/mol) 570.64
Formel vikt 570.64
Kvalitet Research
Fysisk form Powder
För användning med (applikation) Cancer-Kinase/protease
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