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Tocris Bioscience™ Mirabegron
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Produktkod. 18777116
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5 mg
25 mg
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Produktkod. Kvantitet
18777116 25 mg
18798936 5 mg
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Produktkod. 18777116 Leverantör Tocris Bioscience™ Leverantörsnummer 7070/25

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Beskrivning

Potent and selective β3 agonist

Mirabegron is a potent and selective β3-adrenoceptor agonist (EC50 = 22.4 nM). Displays >440-fold selectivity for β3 over β1 and β2 adrenoceptors. Increases cAMP concentration in CHO cells expressing human β3-adrenoceptor. Displays relaxant effect in ex vivo rat bladder muscle preparation precontracted with carbachol (Cat. No. 2810). Decreases frequency of bladder contraction in rats. Also promotes browning of white adipose tissue, reduces body weight, and improves glucose tolerance and insulin sensitivity in mice fed a high fat diet.
TRUSTED_SUSTAINABILITY

Specifikationer

Kemiskt namn eller material 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
CAS 223673-61-8
Kvantitet 25 mg
Molekylformel C21H24N4O2S
Renhet 98%
Produkttitel
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