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ML347, MedChemExpress

MedChemExpress ML347 (LDN193719) is a highly selective ALK1/ALK2 inhibitor. ML347 has IC50 values of 46 and 32 nM against ALK1 and ALK2, respectively, >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-β1.

1058.12 SEK - 6193.13 SEK

Specifications

Chemical Name or Material ML347
CAS 1062368-49-3
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H16N4O
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Description

Description

ML347 (LDN193719) is a highly selective ALK1/ALK2 inhibitor. ML347 has IC50 values of 46 and 32 nM against ALK1 and ALK2, respectively, >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-β1.
Specifications

Specifications

ML347
Yellow
C22H16N4O
DMSO : 10 mg/mL (28.38 mM; Need ultrasonic)
352.39
99.85%
Solid
1062368-49-3
Research
LDN 193719
COC1=CC=C(C2=CN3C(N=C2)=C(C4=C5C=CC=NC5=CC=C4)C=N3)C=C1
352.39
Research
Cancer-Kinase/protease
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Safety and Handling

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

Documents

Product Certifications

Research purposes only

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