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MLN51/CASC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | MLN51/CASC3 |
---|---|
Concentration | 0.33 mg/mL |
Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16898084
|
Proteintech
18047-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 23-04-2024 Log in to see stock. |
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16888084
|
Proteintech
18047-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 23-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.Specifications
MLN51/CASC3 | |
Immunocytochemistry, Immunofluorescence, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
O15234, Q8K3W3, Q8K3X0 | |
192160, 22794, 259170 | |
MLN51/CASC3 Fusion Protein Ag12694 | |
Primary | |
-20°C | |
CASC3 |
0.33 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
BTZ, CASC3, MLN 51, MLN51, Protein barentsz, Protein CASC3 | |
Casc3 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |