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Invitrogen™ Monkey sPECAM-1 Platinum ELISA Kit

For the quantitative detection of soluble monkey platelet endothelial cell adhesion molecule-1.

Brand:  Invitrogen™ BMS651TEN

Additional Details : Weight : 0.23750kg

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Product Code. 15502107

  • 29350.00 SEK / Pack of 10


Estimated Shipment date
from Supplier 27-08-2019
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Includes: Aluminium pouch(es) with a Microwell Plate coated with Monoclonal Antibody (murine) to monkey sPECAM-1
HRP-Conjugate anti-monkey-sPECAM-1 monoclonal (murine) antibody
Monkey sPECAM-1 Standard
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Sample Diluent (buffered protein matrix)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. The N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. Further, CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. CD31 is one of key regulatory molecules in the vascular system. CD31 induces susceptibility to atherosclerosis and this cell adhesion molecule is required for leukocyte migration under most inflammatory conditions. Antibodies to CD31 is of value in the study of benign and malignant vascular tumors.
Specifications

Specifications

0.48-30.0 U/mL
ELISA
Colorimetric Microplate Reader
ELISA
RUO
Serum, Supernatants
Serum (10μL), Supernatants (10μL)
2-8°C
3 hr 10 min
PECAM1
10%
HRP
HRP
101003471
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Controls, Adhesive Plate Covers
10 x 96 tests
0.06 U/mL
10μL
Monkey
1 hr 20 min
Baboon
Leukocyte surface protein, CD31, EndoCAM, HEC7
2%
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