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Gibco™ Mouse GM-CSF Recombinant Protein, PeproTech®
Beskrivning
Recombinant Murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
Specifikationer
Specifikationer
| Tillträdesnummer | P01587 |
| För användning med (applikation) | ELISA, Functional Assay, Western Blot |
| Formulering | protein with no preservative |
| Gen-ID (Entrez) | 12981 |
| Molekylvikt (g/mol) | 14.2 kDa |
| Namn | Mouse GM-CSF |
| Kvantitet | 100 μg |
| Källa | E. coli |
| Regulatorisk status | RUO |
| Endotoxinkoncentration | <1 EU/ μg |
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Produkttitel
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