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Mouse IgG2b kappa Isotype Control (eBMG2b), Super Bright™ 702, eBioscience™, Invitrogen™
Mouse Isotype Control
1542.00 SEK - 3290.00 SEK
Specifications
Antigen | Mouse IgG2b kappa |
---|---|
Clone | eBMG2b |
Conjugate | Super Bright 702 |
Form | Liquid |
Host Species | Mouse |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15875743
|
Affymetrix eBioscience
67-4732-82 |
100μg |
3290.00 SEK
100µg |
Estimated Shipment: 27-05-2024 Log in to see stock. |
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15865743
|
Affymetrix eBioscience
67-4732-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
The isotype of a primary antibody and the application it is being used in can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. Isotype control antibodies can act as negative controls to help differentiate non-specific background signal from specific antibody signal because they have no relevant specificity to a target antigen. While isotype controls are most commonly used in flow cytometry, they are useful in other applications such as chromatin immunoprecipitation (ChIP), immunohistochemistry, and gel shifts. Isotype controls should match with the primary antibody species and isotype so that the level of specific staining by the primary antibody may be accurately determined. If using directly labeled primary antibodies, the isotype control works best if conjugated with the same label as the test antibody.
Mouse IgG2b is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the third most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG2b is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG2b is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry. It is also used in therapeutic applications, such as immunotherapy and vaccine development.Specifications
Mouse IgG2b kappa | |
Super Bright 702 | |
Mouse | |
PBS with BSA and 0.09% sodium azide; pH 7.2 | |
Isotype Control (Primary) |
eBMG2b | |
Liquid | |
RUO | |
IgG2b κ | |
Affinity chromatography |