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Gibco™ Mouse IL-3 Recombinant Protein

Produktkod. 10670154
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Kvantitet:
1 mg
10 μg
100 μg
25 μg
Förpackningsstorlek:
Varje
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For Research Use Only. All usage must comply with product instructions.

Produktkod. 10670154

Brand: Gibco™ PMC0035

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Denna artikel kan inte returneras. Se returpolicy

For Research Use Only. All usage must comply with product instructions.

Beskrivning

Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in deionized water to 0.1-1.0 mg/mL to regain full activity. Apportion the reconstituted protein into working aliquots and store at ≤-20°C. Make any further dilutions of the reconstituted protein in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA. Storage: Store the lyophilized protein at 2-8°C or -20°C for long term storage, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C. Avoid repeated freeze-thaw cycles.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P01586
För användning med (applikation) Bioactivity
Formulering Protein with no preservative
Gen-ID (Entrez) 16187
Molekylvikt (g/mol) 16.1 kDa
Namn Mouse IL-3
Reningsmetod Purified
Kvantitet 25 μg
Förvaringskrav 4°C
Regulatorisk status RUO
Endotoxinkoncentration <0.1 EU/μg
Gene Alias BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
Vanligt namn IL-3
Gensymbol IL3
Biologisk aktivitet ED50 < 0.1 ng/mL; determined by the dose-dependent proliferation of NFS-60 cells.
Produkttyp Protein
Konjugera Unconjugated
Art Mouse
Rekombinant Recombinant
Sekvens ASISGRDTHR LTRTLNCSSI VKEIIGKLPE PELKTDDEGP SLRNKSFRRV NLSKFVESQG EVDPEDRYVI KSNLQKLNCC LPTSANDSAL PGVFIRDLDD FRKKLRFYMV HLNDLETVLT SRPPQPASGS VSPNRGTVEC
Innehåll och lagring 4°C
Klassificering Carrier-Free
Aktivitet ED50 < 0.1 ng/mL; determined by the dose-dependent proliferation of NFS-60 cells.
Endotoxinnivå <0.1 ng/μg
Frakt skick Wet Ice
Uttryckssystem E. coli
Proteinfamilj Cytokines & Receptors
Proteinform Recombinant, Ligand
Form Lyophilized
Protein subtyp Interleukins
Forskningskategori Immunology
Produktlinje Gibco
Renhet eller kvalitetsklass >95% by SDS-PAGE
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