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R&D Systems™ Mouse TEM8/ANTXR1 (NP_473382) VersaClone cDNA
Beskrivning
- Also known as: Tem8; Antrx1; 2310008J16Rik; 2810405N18Rik
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer.
- It has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax.
- The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to ANTXR1 mediates delivery of toxin components to the cytosol of cells.
- Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
- The TEM8/ANTXR1 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
- For reasearch use only. Not for use in humans.
Specifikationer
Specifikationer
| Gen | mAntxr1sity |
| Tillträdesnummer | NP_473382 |
| Koncentration | 10 μg at 0.2 μg/μL |
| Formulering | cDNA is provided in 10 mM Tris-Cl, pH 8.5 |
| Infoga typ | 1702 bp |
| Gen-ID (Entrez) | 84168 |
| Innehåll och lagring | Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Art | Mouse |
| Kvantitet | 10 μg |
Produkttitel
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