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MPP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 17710-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16877644

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

MPP5
0.18 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N3R9, Q9JLB2
MAGUK p55 subfamily member 5, MPP5, PALS1
Rabbit
IgG
20 μL
-20°C
Primary
314259, 56217, 64398
Western Blot, Immunoprecipitation
Unconjugated
MPP5
Liquid
Mpp5
MPP5 Fusion Protein Ag12010
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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