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MSL1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24373-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16822845

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at ′Lys-16′ (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at ′Lys-34′ (H2BK34Ub). This modification in turn stimulates histone H3 methylation at ′Lys-4′ (H3K4me) and ′Lys-79′ (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
Specifications

Specifications

MSL1
0.32 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q68DK7
hMSL1, Male specific lethal 1 homolog, Male specific lethal 1 like 1, MSL 1, MSL1, MSL1 like 1, MSL1L1
Rabbit
IgG
20 μL
-20°C
Primary
339287
Western Blot
Unconjugated
MSL1
Liquid
MSL1
MSL1 Fusion Protein Ag18024
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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