missing translation for 'onlineSavingsMsg'
Learn More

MTA2 Mouse anti-Human, Mouse, Clone: 2G12G4, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66195-1-IG-20UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16887845

  • 1355.00 SEK / 20µL
Estimated Shipment: 23-03-2023
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Specifications

Specifications

MTA2
Monoclonal
1.4 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O94776, Q9R190
MTA2
MTA2 Fusion Protein Ag11713
20 μL
Primary
Mouse, Human
Antibody
IgG2b
Immunofluorescence, Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
2G12G4
Unconjugated
MTA2
Metastasis associated 1 like 1, MTA1 L1 protein, MTA1L1, MTA2, PID
Mouse
Protein A
RUO
23942, 9219
-20°C
Liquid
Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers