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MTA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 17554-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827464

  • 3313.85 SEK / 150µL
Estimated Shipment: 08-12-2021

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Description

Description

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Specifications

Specifications

MTA2
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O94776, Q9R190
Metastasis associated 1 like 1, MTA1 L1 protein, MTA1L1, MTA2, PID
Rabbit
IgG
150 μL
-20°C
Primary
23942, 361724, 9219
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
MTA2
Liquid
Mta2
MTA2 Fusion Protein Ag11713
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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