mTOR Mouse anti-Human, Mouse, Clone: F11, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-2190-82
Additional Details : Weight : 0.01000kg
DescriptionPurity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered. Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.
|PBS with 0.09% sodium azide; pH 7.2|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
For Research Use Only.