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mTOR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20657-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16880225

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Description

Description

The antibody is specific to MTOR.

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.
Specifications

Specifications

mTOR
Polyclonal
Unconjugated
MTOR
FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, MTOR, RAFT1, Rapamycin target protein 1, RAPT1
Rabbit
Antigen Affinity Chromatography
RUO
2475, 56717, 56718
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P42345, P42346, Q9JLN9
Mtor
Peptide
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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