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N-Acetyl-D-mannosamine, 98%, Thermo Scientific™

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Quantity:
1g
5g
Packaging:
Glass bottle
This item is not returnable. View return policy
7772-94-3
C8H17NO7
239.22
MFCD00149493,MFCD00046758,MFCD00149493,MFCD00069808
VVQPUTSNIMAJPT-UHFFFAOYNA-N
n-acetylmannosamine
11908605
N-[(2R,3S,4S,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
O.CC(=O)NC1C(O)OC(CO)C(O)C1O
This item is not returnable. View return policy
7772-94-3
C8H17NO7
239.22
MFCD00149493,MFCD00046758,MFCD00149493,MFCD00069808
VVQPUTSNIMAJPT-UHFFFAOYNA-N
n-acetylmannosamine
11908605
N-[(2R,3S,4S,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
O.CC(=O)NC1C(O)OC(CO)C(O)C1O

N-Acetyl-D-mannosamine (ManNAc), CAS # 7772-94-3, is a monosaccharide sialic acid precursor.

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
• N-Acetyl-D-mannosamine (ManNAc) is a precursor used to synthesize N-acetylneuraminic acid, the most common physiologic sialic acid present in humans and other mammals
• Sialic acids are terminal sugars on glycoconjugates that can modify biochemistry of glycoproteins and lipids, mediate cellular adhesion, and act as immune regulators
• Defects in sialic acid biosynthesis are associated with a number of pathologies
• Sialic acids are often found at increased expression levels on tumor cell surfaces
Applications
• As a sialic acid precursor, N-Acetyl-D-mannosamine can be used in many glycoengineering applications, such as modifying immune cell activity, imaging glycans, or blocking pathogen binding
• N-Acetyl-D-mannosamine hasbeen used in preclinical laboratory studies as a treatment for hereditary inclusion body myopathy, a progressive neuromuscular disease via increased sialylation of podocalyxin
• N-Acetyl-D-mannosamine has been used in laboratory studies to induce IgG sialylation and prevent obesity-induced hypertension in mice following high-fat diet
CAS Min % 97.5
CAS Max % 100.0
Color White
Assay Percent Range 98%
Infrared Spectrum Authentic
Packaging Glass bottle
Quantity 5g
Formula Weight 221.21
Physical Form Crystalline Powder
Percent Purity ≥97.5%
Water 11% max.
Chemical Name or Material N-Acetyl-D-mannosamine
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Product Identifier
  • N-Acetyl-D-mannosamine

RUO – Research Use Only