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N-Ethylmaleimide, 98+%, Thermo Scientific Chemicals

Catalog Number p-7043349
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Quantity:
10 g
50 g
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
128-53-0
C6H7NO2
125.127
MFCD00005509
HDFGOPSGAURCEO-UHFFFAOYSA-N
n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide
4362
CHEBI:44485
1-ethylpyrrole-2,5-dione
CCN1C(=O)C=CC1=O
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
128-53-0
C6H7NO2
125.127
MFCD00005509
HDFGOPSGAURCEO-UHFFFAOYSA-N
n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide
4362
CHEBI:44485
1-ethylpyrrole-2,5-dione
CCN1C(=O)C=CC1=O

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.
TRUSTED_SUSTAINABILITY
Melting Point 43°C to 46°C
Boiling Point 209°C to 211°C
Flash Point 73°C (163°F)
Odor Pungent
Quantity 10 g
UN Number UN2928
Beilstein 112448
Sensitivity Light sensitive
Merck Index 14,3822
Solubility Information Soluble in ethanol,water,chloroform,methanol and toluene.
Formula Weight 125.13
Percent Purity ≥98%
Chemical Name or Material N-Ethylmaleimide
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Product Identifier
  • N-Ethylmaleimide
Signal Word
  • Danger
Hazard Category
  • Acute toxicity Category 2
  • Skin corrosion/irritation Category 1 B
  • Acute toxicity Category 4
  • Skin sensitiser Category 1
Hazard Statement
  • H300-Fatal if swallowed.
  • H312-Harmful in contact with skin.
  • H314-Causes severe skin burns and eye damage.
  • H317-May cause an allergic skin reaction.
Precautionary Statement
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

RUO – Research Use Only

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