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N,O-Bis(trimethylsilyl)acetamide, 95%, Thermo Scientific Chemicals

Catalog Number p-7043317
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Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
10416-59-8
C8H21NOSi2
203.43
MFCD00008270
SIOVKLKJSOKLIF-UHFFFAOYSA-N
n,o-bis trimethylsilyl acetamide, trimethylsilyl 1z-n-trimethylsilylethanimidate
6913588
CC(O[Si](C)(C)C)=N[Si](C)(C)C
This item is not returnable. View return policy
10416-59-8
C8H21NOSi2
203.43
MFCD00008270
SIOVKLKJSOKLIF-UHFFFAOYSA-N
n,o-bis trimethylsilyl acetamide, trimethylsilyl 1z-n-trimethylsilylethanimidate
6913588
CC(O[Si](C)(C)C)=N[Si](C)(C)C

N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.

Solubility
Miscible with many nonpolar and polar aprotic solvents.

Notes
Air and moisture sensitive. Incompatible with strong oxidizing agents, water and acids.
TRUSTED_SUSTAINABILITY
Boiling Point 71°C to 73°C (35mmHg)
Melting Point -24°C
Quantity 5 g
UN Number UN2920
Beilstein 1306669
Flash Point 42°C (107°F)
IUPAC Name trimethylsilyl (1E)-N-trimethylsilylethanimidate
Formula Weight 203.43
Percent Purity 95%
Chemical Name or Material N,O-Bis(trimethylsilyl)acetamide

RUO – Research Use Only

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