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NAT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 19188-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.Specifications
NAT1 | |
Polyclonal | |
Unconjugated | |
NAT1 | |
AAC1, Arylamide acetylase 1, MNAT, N acetyltransferase type 1, NAT 1, NAT1, NATI | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
116631, 17960, 9 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot | |
0.31 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P18440, P50294, P50297 | |
Nat1 | |
NAT1 Fusion Protein Ag6280 | |
20 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |