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NAT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19188-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16878914

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.
Specifications

Specifications

NAT1
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P18440, P50294, P50297
AAC1, Arylamide acetylase 1, MNAT, N acetyltransferase type 1, NAT 1, NAT1, NATI
Rabbit
IgG
20 μL
-20°C
Primary
116631, 17960, 9
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
Unconjugated
NAT1
Liquid
Nat1
NAT1 Fusion Protein Ag6280
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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