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Tocris Bioscience™ NDT 9513727
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Produktkod. 18013792
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Produktkod. Kvantitet
18013792 10 mg
18025782 50 mg
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Produktkod. 18013792 Leverantör Tocris Bioscience™ Leverantörsnummer 3333/10

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Beskrivning

Potent, selective human C5a receptor negative allosteric modulator (NAM)

Potent C5a receptor (C5aR) negative allosteric modulator (NAM) (IC50 = 11.6 nM); selective for human C5aR (IC50 values for rat and mouse C5aR are > 10 μM). Exhibits inverse agonist pharmacokinetics. Blocks degranulation response in C5a-stimulated U937 cells (IC50 = 7.1 nM). Exhibits selectivity for primate and gerbil receptor over other species. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 439571-48-9
Molekylformel C36H35N3O4

Specifikationer

Kemiskt namn eller material NDT 9513727
Kvantitet 10 mg
Formel vikt 573.68
Renhet >98%
Molekylvikt (g/mol) 573.693
Produkttitel
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