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NDUFAF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13891-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappa-B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.Specifications
NDUFAF2 | |
Polyclonal | |
Unconjugated | |
NDUFAF2 | |
B17.2 like, B17.2L, mimitin, Mimitin, mitochondrial, MMTN, NDUFA12 like protein, NDUFA12L, NDUFAF2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
361894, 75597, 91942 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8N183 | |
Ndufaf2 | |
NDUFAF2 Fusion Protein Ag4853 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |