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NDUFAF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13891-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16822304

  • 3313.85 SEK / 150µL
Estimated Shipment: 08-12-2021

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Description

Description

Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappa-B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.
Specifications

Specifications

NDUFAF2
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N183
B17.2 like, B17.2L, mimitin, Mimitin, mitochondrial, MMTN, NDUFA12 like protein, NDUFA12L, NDUFAF2
Rabbit
IgG
150 μL
-20°C
Primary
361894, 75597, 91942
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
NDUFAF2
Liquid
Ndufaf2
NDUFAF2 Fusion Protein Ag4853
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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