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Thermo Scientific™ Lab Vision™ NFκ B/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody.

Brand:  Thermo Scientific™ RB-1638-R7

Additional Details : Weight : 1.00000kg

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Product Code. 12613107

  • 3720.00 SEK / 7mL


Estimated Shipment date
from Supplier 16-03-2020
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Description

Description

NFκ B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodimer is present in the cytoplasm in inactive form bound to its inhibitor, IdeltaB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFκB which goes to the nucleus inducing gene expression. NFκB was originally identified as transcriptional activator for kappa light chain gene in B cells.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drosophila, Xenopus. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human NFκB protein

Molecular Weight: 65kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

NFkappaB/p65 (Rel A) Ab-1
Polyclonal
Ready-to-use for IHC (UVLP)
Rabbit
IgG
RUO
Primary
Polyclonal
Western Blot
Unconjugated
Prediluted
A synthetic peptide from the C-terminus of human NFkappaB protein
7mL
Transcription Regulation
Primary
Bovine, Canine, Drosophila, Hamster, Human, Murine, Porcine, Rabbit, Rat
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