Thermo Scientific™ Lab Vision™ NFκ B/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody
Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody.
Brand: Thermo Scientific™ RB-1638-R7
Additional Details : Weight : 1.00000kg
DescriptionNFκ B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodimer is present in the cytoplasm in inactive form bound to its inhibitor, IdeltaB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFκB which goes to the nucleus inducing gene expression. NFκB was originally identified as transcriptional activator for kappa light chain gene in B cells.
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drosophila, Xenopus. Others not known.
Immunogen: A synthetic peptide from the C-terminus of human NFκB protein
Molecular Weight: 65kDa
Positive Control: Jurkat cells
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|NFkappaB/p65 (Rel A) Ab-1|
|Ready-to-use for IHC (UVLP)|
|A synthetic peptide from the C-terminus of human NFkappaB protein|
|Bovine, Canine, Drosophila, Hamster, Human, Murine, Porcine, Rabbit, Rat|