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Invitrogen™ NFkB p100 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582349
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Beskrivning
Immunogen sequence: LLNAAQNTME PPLTPPSPAG PGLSLGDTAL QNLEQLLDGP EAQGSWAELA ERLGLRSLVD TYRQTTSPSG SLLRSYELAG GDLAGLLEAL SDMGLEEGVR LLRGPETRDK LPSTEVKEDS AYGSQSVEQE A Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 93%.
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Specifikationer
| NFkB p100 | |
| Polyclonal | |
| Unconjugated | |
| Nfkb2 | |
| CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; Lyt10; LYT-10; NF kappaB2; NF-kappaB2; NF-kB p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4791 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q00653 | |
| Nfkb2 | |
| Recombinant protein corresponding to Human NFKB2. Recombinant protein control fragment (Product # RP-102320). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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