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iNOS Monoclonal Antibody (CXNFT), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1376.00 SEK - 3345.00 SEK

Specifications

Antigen iNOS
Clone CXNFT
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunocytochemistry, Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15530227
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Affymetrix eBioscience
53-5920-80
25 μg
1376.00 SEK
25µg
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15540227
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Affymetrix eBioscience
53-5920-82
100 μg
3345.00 SEK
100µg
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Description

Description

Description: This CXNFT monoclonal antibody reacts to mouse NOS2 (inducible NOS, iNOS). Nitric oxide synthase enzymes catalyze the formation of nitric oxide from L-arginine through an NADPH- and oxygen-dependent mechanism. There are three isoforms of NOS that are encoded by three separate genes. NOS1 (neuronal NOS, nNOS) and NOS3 (endothelial NOS, eNOS) are constitutively expressed, while NOS2 is induced in response to bacterial endotoxins and inflammatory cytokines such as IFN gamma and TNF alpha. NOS2 is expressed by myeloid-derived suppressor cells and M1 macrophages but not alternatively activated M2 macrophages. NOS enzymes are functionally active only when they form homodimers, and dimerization of NOS2 occurs at steady-state concentrations of free Ca2+ such that NOS2 is functionally active when it is produced. Applications Reported: This CXNFT antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This CXNFT antibody has been tested by intracellular staining and flow cytometric analysis of stimulated mouse thioglycolate-elicited peritoneal exudate cells using the intracellular Fixation and Permeabilization Buffer Set (cat. 88-8824) and protocol. The Foxp3/Transcription Factor Staining Buffer Set (cat. 00-5523) may also be used with similar results. This can be used at less than or equal to 0.06 μg per test.

iNOS Monoclonal antibody specifically detects iNOS in Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry, Western Blot.
Specifications

Specifications

iNOS
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Nos2
Primary
4° C, store in dark, DO NOT FREEZE!
Nos2
CXNFT
Flow Cytometry, Immunocytochemistry, Western Blot
Alexa Fluor 488
Rat
Mouse
P29477
18126
IgG2a κ
Affinity chromatography
Antibody
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