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NR4A1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25851-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16824415

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. NGFI-B-alpha is expressed in brain, adrenal, thyroid, liver, testis, ovary, thymus, muscle, lung and prostate. Its expression is induced in response to various stress stimuli and growth factors. The encoded protein acts as a nuclear transcription factor involved in mediating apoptotic signaling in thymocytes and tumor cells, as well as having a role in signaling in the hypothalamic-pituitary axis. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Three transcript variants encoding two distinct isoforms have been identified for this NR4A1. Variant (3), also known as TRC beta, contains multiple differences compared to variant 1. The resulting isoform b contains a shorter and distinct C-terminus compared to isoform a. RXR has been shown to be a partner for NR4A1.
Specifications

Specifications

NR4A1
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P22736
Early response protein NAK1, GFRP1, HMR, N10, NAK 1, NAK1, NGFIB, NR4A1, NUR77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST 59, Testicular receptor 3, TR3
Rabbit
IgG
20 μL
-20°C
Primary
3164
Western Blot
Unconjugated
NR4A1
Liquid
NR4A1
NR4A1 Fusion Protein Ag23088
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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