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Invitrogen™ NSD2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA540725
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Beskrivning
Peptide sequence: KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG Sequence homology: Dog: 93%; Guinea Pig: 88%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 76%; Rat: 86%.
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
Specifikationer
| NSD2 | |
| Polyclonal | |
| Unconjugated | |
| NSD2 | |
| 5830445G22Rik; 9430010A17Rik; AW555663; C130020C13Rik; D030027O06Rik; D930023B08Rik; Histone-lysine N-methyltransferase NSD2; histone-lysine N-methyltransferase NSD2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; Kiaa1090; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2; mKIAA1090; MMSET; multiple myeloma SET domain containing protein type III; multiple myeloma SET domain-containing protein; NSD2; nuclear receptor binding SET domain protein 2; nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; Protein trithorax-5; putative histone-lysine N-methyltransferase NSD2-like protein; REIIBP; RGD1565590; trithorax/ash1-related protein 5; TRX5; WHS; Whsc1; Whsc1l; Wolf-Hirschhorn syndrome candidate 1; Wolf-Hirschhorn syndrome candidate 1 (human); Wolf-Hirschhorn syndrome candidate 1 protein; Wolf-Hirschhorn syndrome candidate 1 protein homolog | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 7468 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| O96028 | |
| NSD2 | |
| Synthetic peptide directed towards the N-terminal of human WHSC1 (aa 219-268). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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