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OBFC2B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14809-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.Specifications
| OBFC2B | |
| Polyclonal | |
| Unconjugated | |
| NABP2 | |
| hSSB1, OBFC2B, Sensor of ssDNA subunit B1, SOSS B1, SOSS complex subunit B1, SSB1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 362813, 69917, 79035 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q3SWT1, Q8R2Y9, Q9BQ15 | |
| Nabp2 | |
| OBFC2B Fusion Protein Ag6532 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |