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OCT3/4 Rat anti-Human, Mouse, Clone: EM92, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5841-80

Additional Details : Weight : 0.01000kg

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Product Code. 15237507

  • 1390.00 SEK / 25µg


Estimated Shipment date
from Supplier 27-03-2019
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Description

Description

Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered. POU5F1, also commonly known as Oct-4, is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. The role of POU5F1 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing POU5F1, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
Specifications

Specifications

OCT3/4
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q01860, P20263
Octamer-binding transcription factor 3 antibody, Oct-3, OCT3, POU domain class 5 transcription factor 1 antibody, Oct-4, OTF3 antibody.
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Immunohistochemistry, Western Blot
EM92
Unconjugated
POU5F1
Liquid
POU5F1
IgG2a, kappa
25 μg
4° C
Primary
18999, 5460
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