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Tocris Bioscience™ Ondansetron hydrochloride
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Produktkod. 18782554
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18782554 10 mg
18722704 50 mg
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Produktkod. 18782554 Leverantör Tocris Bioscience™ Leverantörsnummer 2891/10

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Beskrivning

Selective 5-HT3 antagonist

Ondansetron hydrochloride is a selective 5-HT3 receptor antagonist (Ki = 6.16 nM). Also an inhibitor of human multidrug and toxin extrusion (MATE) transporter 1 (IC50 = <10-160 nM). Ondansetron blocks 5-HT-evoked transient inward currents (IC50 = 0.1 nM) in human recombinant h5-HT3A receptors. In an animal model of Parkinson's disease, Ondansetron reduces both the severity of dyskinesia and psychosis-like behaviors. Antiemetic; prevents emesis induced by cytotoxic drugs and radiation.
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Kemiska identifierare

CAS 99614-01-4
Molekylformel C18H20ClN3O

Specifikationer

Kemiskt namn eller material Ondansetron hydrochloride
Kvantitet 10 mg
Formel vikt 329.83
Renhet >99%
Molekylvikt (g/mol) 329.83
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