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ONX-0914, MedChemExpress

Produktkod. 16491717
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16468257 5 mg 5mg
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Produktkod. 16491717 Leverantör Medchem Express Leverantörsnummer HY13207

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Beskrivning

MedChemExpress ONX-0914 (PR-957) is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1.

ONX-0914 (PR-957) is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1.

Specifikationer

Kemiskt namn eller material ONX-0914
CAS 960374-59-8
Färg White
Anteckningar om renhetsgrad Research
Molekylformel C31H40N4O7
Kvantitet 50 mg
Synonym PR-957
Löslighetsinformation DMSO : ≥ 35 mg/mL (60.28 mM)
LEDER O=C(N[C@@H](C)C(N[C@@H](CC1=CC=C(OC)C=C1)C(N[C@@H](CC2=CC=CC=C2)C([C@]3(C)OC3)=O)=O)=O)CN4CCOCC4
Molekylvikt (g/mol) 580.67
Formel vikt 580.67
Procent renhet 95.03%
Kvalitet Research
Fysisk form Solid
För användning med (applikation) COVID-19-immunoregulation
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Research purposes only

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