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p38 MAPK Mouse anti-Human, Porcine, Clone: 1A1C2, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66234-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827925

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

The p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation, and other signals. p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.
Specifications

Specifications

p38 MAPK
1A1C2
Unconjugated
MAPK14
Liquid
MAPK14
p38 MAPK Fusion Protein Ag5797
Protein A
RUO
Antibody
Monoclonal
Porcine, Human
Western Blot, Immunohistochemistry (Paraffin)
1.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q16539
CSAID binding protein, CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, Mxi2, p38, p38 MAPK, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A
Mouse
IgG2b
20 μL
-20°C
Primary
100156630, 1432
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