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STEMCELL Technologies Paclitaxel
Beskrivning
- Paclitaxel is a diterpene alkaloid originally isolated from the bark of the Pacific Yew tree (Taxus brevifolia)
- It binds to and stabilizes microtubules, preventing their reorganization during cell division, which leads to cell cycle arrest
- Paclitaxel has antitumorigenic properties and has been used as a chemotherapeutic compound (Rowinsky et al.) Many pathways have been implicated in Paclitaxel-induced apoptosis, including c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK), p38 mitogen-activated protein kinase (MAPK), and protein kinase A (PKA; Wang et al.; Reshkin et al.)
Specifikationer
Specifikationer
| CAS | 33069-62-4 |
| Synonym | NSC 125973 |
| Kvantitet | 100 mg |
| Molekylformel | C47H51NO14 |
| Renhet | ≥98% |
Produkttitel
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