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Paclitaxel, 99.5+%, Thermo Scientific™
Paclitaxel (CAS # 33069-62-4) is a microtubule inhibitor produced from the extract of the Pacific yew tree.
Brand: Thermo Scientific Alfa Aesar J62734.MC
| Kvantitet | 100mg |
|---|
Produktkod. 15495039
-
1869.49 SEK
1678.65 SEK / 100mg
Save 190.84 SEK
10% Av
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Beskrivning
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
- Paclitaxel is a tetracyclic diterpenoid isolated from the Pacific yew, Taxus brevifolia
- Paclitaxel acts as an antineoplastic agent by binding tubulin and preventing cell division
- Paclitaxel may also bind Bcl-2 and lead to disinhibition of apoptosis
Application
- Paclitaxel is used in the study of lung, breast, and ovarian cancers; it may be useful in the research of other cancer types
- It is suitable for cell culture, biochemistry, and molecular biology applications
Kemiska identifierare
| 33069-62-4 | |
| 853.92 | |
| RCINICONZNJXQF-VAZQATRQSA-N | |
| 133640187 | |
| CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 |
| C47H51NO14 | |
| MFCD00869953 | |
| paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel | |
| (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate |
Specifications
| Paclitaxel | |
| C47H51NO14 | |
| 100mg | |
| 14,6982 | |
| Soluble in DMSO (200mg/ml) or ethanol (40mg/ml); Soluble in dimethylsulfoxide,methanol,ethanol,acetonitrile,cremophor and dimehtylsulfamide; Sparingly soluble in aqueous buffer. | |
| CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 | |
| 853.92 | |
| 853.91 |
| 33069-62-4 | |
| MFCD00869953 | |
| 1420457 | |
| paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel | |
| RCINICONZNJXQF-VAZQATRQSA-N | |
| (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate | |
| 133640187 | |
| ≥99.5% |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Paclitaxel
Signal Word
- Fara
Hazard Category
- FARA FÖR SKADLIGA LÅNGTIDSEFFEKTER (FÖR VATTENMILJÖN) Kategori: kronisk 4
- Allvarlig ögonskada/ögonirritation Kategorija 1
- Reproduktionstoxicitet Kategorija 2
- Frätande eller irriterande verkan på hud Kategori 2
- Preobcutljivost koze Kategorija 1
- Specifik organtoxicitet Kategorija 3
Hazard Statement
- H315-Irriterar huden.
- H317-Kan orsaka allergisk hudreaktion.
- H318-Orsakar allvarliga ögonskador.
- H335-Kan orsaka irritation i luftvägarna.
- H361-Misstänks kunna skada fertiliteten eller det ofödda barnet.
- H413-Kan ge skadliga långtidseffekter på vattenlevande organismer.
Precautionary Statement
- P280-Använd skyddshandskar/skyddskläder/ögonskydd/ansiktsskydd.
- P302+P352-VID HUDKONTAKT: Tvätta med mycket vatten/.
- P304+P340-VID INANDNING: Flytta personen till frisk luft och se till att andningen underlättas.
- P305+P351+P338-VID KONTAKT MED ÖGONEN: Skölj försiktigt med vatten i flera minuter. Ta ur eventuella kontaktlinser om det går lätt. Fortsätt att skölja.
- P310-Kontakta genast GIFTINFORMATIONSCENTRALEN/läkare .
Supplemental information
- MIXTURE LIST-Contain: Paclitaxel
Product Title
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