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DiscoverX PathHunter™ eXpress GLP1R CHO-K1 β-Arrestin-1 GPCR Assay

Produktkod. 17373999
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Kvantitet:
1 000 dp (10 x 96-brunnar)
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Produktkod. Kvantitet
17373999 1 000 dp (10 x 96-brunnar)
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Produktkod. 17373999 Leverantör DiscoverX Leverantörsnummer 930914E2CP2L

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Beskrivning

The PathHunter™ eXpress GLP1R CHO-K1 β-Arrestin-1 GPCR Assay measures GLP1R (ARR1) (GPCR) activity via recruitment of β-Arrestin-1. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ GLP1R (ARR1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. exendin-4) based activation of GLP1R GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged GLP1R and EA-tagged β-Arrestin-1. Activation of GLP1R stimulates the recruitment of β-Arrestin-1 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifikationer

Analysinträde β-arrestin recruitment
För användning med (applikation) Assay-Ready eXpress Kits
Primär agonist Exendin-4
Kvantitet 1 000 dp (10 x 96-brunnar)
Målinträde GLP1R (ARR1)
Celllinje CHO-K1
Mål GLP1R (ARR1)
Produkttitel
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