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DiscoverX PathHunter™ eXpress P2RY2 U2OS β-Arrestin GPCR Assay

Produktkod. 17373549
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Kvantitet:
1 000 dp (10 x 96-brunnar)
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Produktkod. Kvantitet
17373549 1 000 dp (10 x 96-brunnar)
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Produktkod. 17373549 Leverantör DiscoverX Leverantörsnummer 930628E3CP5L

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Beskrivning

The PathHunter™ eXpress P2RY2 U2OS β-Arrestin GPCR Assay measures P2RY2 (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ P2RY2 β-Arrestin eXpress Kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. UTP) based activation of P2RY2 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged P2RY2 and EA-tagged β-Arrestin 2. Activation of P2RY2 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifikationer

Analysinträde GPCR
För användning med (applikation) Assay-Ready eXpress Kits
Kvantitet 1 000 dp (10 x 96-brunnar)
Målinträde P2RY2
Celllinje U2OS
Mål P2RY2
Produkttitel
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