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DiscoverX PathHunter™ eXpress TrkA Functional Assay

Produktkod. 17343209
Encompass
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Kvantitet:
200 dp (2 x 96-brunnar)
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Produktkod. Kvantitet
17343209 200 dp (2 x 96-brunnar)
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Produktkod. 17343209 Leverantör DiscoverX Leverantörsnummer 930462E3CP16M

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Descrizione

The PathHunter™ eXpress TrkA Functional Assay measures TrkA receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ eXpress TrkA Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TrkA dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cells overexpress PK-tagged TrkA and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifica

Analysinträde Kinase
För användning med (applikation) Assay-Ready eXpress Kits
Kvantitet 200 dp (2 x 96-brunnar)
Målinträde TrkA
Mål TrkA
Titolo del prodotto
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