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DiscoverX PathHunter™ Tocilizumab Bioassay Kit

Produktkod. 17384289
Encompass
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Kvantitet:
1 000 dp (10 x 96-brunnar)
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17384289 1 000 dp (10 x 96-brunnar)
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Product Code. 17384289 Supplier DiscoverX Supplier No. 931045B300110

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Description

The PathHunter™ Tocilizumab Bioassay Kit measures ligand-induced dimerization of IL-6ST and IL-6R. Bioassay kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ Tocilizumab Bioassay kit provides an easy-to-use cell based assay to determine potency of anti-IL-6R or anti-IL-6 antibodies such as Tocilizumab. This bioassay assesses ligand (e.g. IL-6) induced dimerization of of IL-6ST and IL-6R. receptors. This product uses EFC technology. The cell line included overexpresses IL-6ST target protein fused to PK alongside IL-6R target protein fused to EA. Upon ligand-induced dimerization of IL-6ST and IL-6R , detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.

Specifications

Analysinträde Dimerization
För användning med (applikation) Assay-Ready Bioassay Kits
Kvantitet 1 000 dp (10 x 96-brunnar)
Målinträde IL-6R/IL-6ST
Celllinje U2OS
Mål IL-6R/IL-6ST
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