PAX5, clone: 1H9, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9918-80
Additional Details : Weight : 0.01000kg
Description00-5521) be used for optimal results when using this antibody for intracellular staining and flow cytometric analysis. Applications Reported: This 1H9 antibody has been reported for use in immunoprecipitation, immunoblotting (WB), and immunohistology staining of frozen tissue sections. Applications Tested: This 1H9 antibody has been tested by western blot analysis. This can be used at less than or equal to 5 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered. PAX5 is a member of the paired box (PAX) family of transcription factors. The PAX proteins are important regulators in early development and alterations in the expression of their genes are thought to contribute to neoplastic transformation. PAX5 is the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages, of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis. Mutations in the gene can result in leukemia, acute lymphoblastic 3.
|PBS with 0.09% sodium azide; pH 7.2|
|Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot|
For Research Use Only.