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Invitrogen™ PD-L1 Polyclonal Antibody

Beskrivning
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Specifikationer
Specifikationer
| Antigen | PD-L1 |
| Användningsområden | Flow Cytometry, Western Blot, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 0.5 mg/mL |
| Konjugera | Unconjugated |
| Formulering | TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 |
| Gen | Cd274 |
| Genaccessionsnr. | Q9NZQ7 |
| Gene Alias | A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1 |
| Gensymboler | Cd274 |
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Produkttitel
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