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PDE8A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13956-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16822404

  • 4721.67 SEK / 150µL
Estimated Shipment: 03-04-2024
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Description

Description

PDE8A is a Phosphodiesterase (PDEs), which regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (MIM 2000).
Specifications

Specifications

PDE8A
Polyclonal
Unconjugated
PDE8A
HsT19550, PDE8A, phosphodiesterase 8A
Rabbit
Antigen Affinity Chromatography
RUO
18584, 308776, 5151
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.42 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O60658, O88502
Pde8a
PDE8A Fusion Protein Ag5069
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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