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Gibco™ PeproGMP® Human IL-3 Recombinant Protein, PeproTech®

Produktkod. 30276693 Handla allt Gibco Produkter
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30276693 1 mg
30275259 100 μg
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Produktkod. 30276693 Leverantör Gibco™ Leverantörsnummer GMP200031MG
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Beskrivning

Recombinant Protein

Additional product information and specifications are provided on the Certificate of Analysis. All PeproGMP® products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products. Product use statement: For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P08700
För användning med (applikation) Bioactivity, Control, Western Blot Control
Formatera Lyophilized
Formulering Protein with no preservative
Gen-ID (Entrez) 3562
Molekylvikt (g/mol) 15 kDa
Namn PeproGMP™ Human IL-3
Reningsmetod Purified
Kvantitet 1 mg
Förvaringskrav -20°C or -80°C if preferred
Regulatorisk status GMP
Endotoxinkoncentration ≤0.1 EU/μg
Gene Alias BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
Vanligt namn IL-3
Gensymbol IL3
Biologisk aktivitet Determined by the proliferation of TF-1 cells. PeproGMP Recombinant Human IL-3 ha been tested against the WHO standard NIBSC 91/510.
Produkttyp Protein
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
Innehåll och lagring -20°Cor to +80°C if preferred
Aktivitet Determined by the proliferation of TF-1 cells. PeproGMP Recombinant Human IL-3 has been tested against the WHO standard NIBSC 91/510. Find the International Unit (IU) value <a href='https://www.thermofisher.com/us/en/home/life-science/cell-culture/cell-culture-learning-center/recombinant-protein-information/international-units.html'>here</a>.
Uttryckssystem E. coli
Form Lyophilized
Produktlinje PeproGMP
Renhet eller kvalitetsklass ≥ 98% by SDS-PAGE gel and HPLC analyses.
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